In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously "frozen" patients - young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson's disease, administered L-dopa - the only known effective treatment - and "unfroze" his patient. Dr. Langston determined that th...
Details The Case of the Frozen Addicts
Reviews The Case of the Frozen Addicts
- A fascinating book on the discovery of the MPTP monkey model, "The Case of the Frozen Addicts" follows the frozen addicts that started the investigation, and the reasoning behind the production of the synthetic heroin that made them that way. Langston chronicles the initial discovery and the research it ignited in the years following. The 2014 edition has a follow-up interview with Langston and helps put the book into perspective. The book reads ...
- A caveat: If you are an animal rights advocate, or are sensitive to the suffering of animals, this may not be a good reading choice for you. A large portion of the book is dedicated to animal studies, in which rats and monkeys are intentionally afflicted with Parkinson's disease and then "sacrificed" in order for their brains to be studied.
- I'm assigning excerpts of this to my psychopharmacology students. This book does a decent job of covering the ethical, political, and scientific angles of understanding brain pathologies. The science is accessible for the non-science person. An informative and entertaining read.
- It was surprising how I got drawn into the book and the stories of the addicts. I thought this might be dry or too clinical, making it hard to read and follow but it was great. I learned a lot, while reading an interesting part of our scientific history.
- Really interesting! Well worth the read!
- I found it an excellent as it described what happens to Parkinson's patients who are bedridden and inactive. I liked the through detail it went into describing 6 frozen addicts.